Resources

Setting Priorities in Global Child Health Research Investments: Guidelines for Implementation of the CHNRI Method

Rudan, I. et al.

Provides guidelines for implementing the CHNRI method to systematically set priorities in global child health research investments for funders and policymakers.

Sex And Gender Differences In Neurodegenerative Diseases: Challenges For Therapeutic Opportunities

Bianco et al.

Reviews sex and gender differences in neurodegenerative diseases, highlighting implications for pathogenesis, clinical features, and therapeutic responses to support personalized medicine.

Sex and Gender Differences Research Design for Basic, Clinical, and Population Studies: Essentials for Investigators

Rich-Edwards, J. W. et al.

Summarizes key research design considerations for studying sex and gender differences to enhance scientific rigor in basic, clinical, and population research.

Sex and Gender Equity in Research: Rationale for the SAGER Guidelines and Recommended Use

Heidari, S. et al.

Provides information on the SAGER guidelines, which standardize sex and gender reporting in research to improve transparency and equity in scientific publications.

Sex And Gender Health Educational Tenets: A Report From the 2020 Sex and Gender Health Education Summit

Kling, J. M., et al.

Summarizes four core tenets for integrating sex and gender health concepts into interprofessional health education to guide curriculum development and improve patient care.

Sex And Gender In Research Involving Humans According To The HRA: Recommendations for the Ethical Review of Research Projects

Swissethics

Provides recommendations and practical guidelines for integrating sex and gender considerations in biomedical research protocols for ethical review purposes.

Sex and Gender Specific Health Curriculum

Texas Tech University

Provides open-access educational modules, slides, and resources on sex and gender differences in health to support curriculum integration and improve healthcare education.

Sex Differences In Cardiometabolic Disorders

Gerdts & Regitz-Zagrosek

Provides information on the global burden, epidemiology, and trends of chronic respiratory diseases to inform public health strategies and policy development.

Sex Differences in Health and Disease: A Review of Biological Sex Differences Relevant to Cancer with a Spotlight on Glioma

Massey, S. C. et al.

Summarizes the role of exosomes in cancer progression, focusing on their mechanisms, diagnostic potential, and therapeutic implications for cancer management.

Sex Differences in the Burden of Type 2 Diabetes and Cardiovascular Risk Across the Life Course

Huebschmann, A. et al.

Reviews sex differences in type 2 diabetes prevalence and cardiovascular risk, summarizing epidemiology, mechanisms, and research gaps to inform prevention and management strategies.

Sex Differences in the Prevalence of, and Trends in, Cardiovascular Risk Factors, Treatment, and Control in the United States, 2001 to 2016

Peters, S. A. et al.

Summarizes sex differences in prevalence, treatment, and control of cardiovascular risk factors in US adults from 2001–2016 to inform prevention efforts.

Sex Differences in Tolerability to Anti-Programmed Cell Death Protein 1 Therapy in Patients with Metastatic Melanoma and Non-Small Cell Lung Cancer: Are We All Equal?

Duma, N. et al.

Provides information on sex differences in immune-related adverse events from anti-PD-1 therapy in metastatic melanoma and NSCLC, highlighting higher risk in women.

Sex Differences in Traumatic Brain Injury: What We Know and What We Should Know

Gupte, R. et al.

Summarizes current knowledge and research gaps on sex differences in traumatic brain injury outcomes, comparing human and animal studies to guide future research and clinical care. Note: This summary is based on the abstract and main sections; the full article contains more detailed data.

Sex hormones and immune regulation in ovarian cancer

Zhao et al.

Reviews the interplay between sex hormones and immune regulation in ovarian cancer, detailing mechanisms, therapeutic implications, and future research directions.

Sex influence on cancer immunotherapy efficacy and safety in advanced non-small cell lung cancer (NSCLC): A Canadian institution real-world experience

Cohen et al.

Summarizes real-world data on sex differences in immunotherapy efficacy and safety for advanced NSCLC, highlighting higher immune-related adverse events in females.

Sex- and Gender-Based Pharmacological Response to Drugs

Mauvais-Jarvis, F. et al.

Summarizes pharmacokinetics, pharmacodynamics, and clinical applications of monoclonal antibodies, providing guidance for therapeutic use and drug development.

Sex-Based Differences in the Effect of Digoxin for the Treatment of Heart Failure

Rathore, S. S. et al.

Provides information on sex-based differences in digoxin therapy for heart failure, showing increased mortality risk in women but not men.

Sex-Based Heterogeneity in Response to Lung Cancer Immunotherapy: A Systematic Review and Meta-Analysis

Conforti, F. et al.

Reviews data on sex-based differences in lung cancer immunotherapy efficacy, showing women benefit more from chemo-immunotherapy combinations than men.